Science Alert: Intermittent catheterization for Bladder management – can infections be avoided?

January 30, 2018

Intermittent catheterization is today a first choice therapy for people with neurogenic or non-neurogenic lower urinary tract dysfunction related to incomplete bladder emptying. In recent years, the evidence for the safety of catheter reuse has been debated. 

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Topics: Clean Intermittent Catheterization (CIC), Neurogenic bladder, Lower Urinary Tract Symptoms (LUTS)

Science Alert: Using cranberry to prevent urinary tract infection (UTI) – an old remedy with new clinical evidence

January 2, 2018

The Cochrane review from 2013 by Jepson et al. 2013 was unable to recommend cranberry juice to prevent urinary tract infection (UTI). They furthermore identified a lack of evidence for the efficacy of other cranberry preparations (such as powders). New studies are, however, continuously added to the total weight of clinical evidence and the latest examples suggest that there may be benefits in this traditional remedy.

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Topics: Science Alert, Urinary Tract Infection (UTI)

Science Alert: Spinal cord injury (SCI) research and the International Spinal Cord Society (ISCoS)

December 26, 2017

The term spinal cord injury (SCI) comprises a wide range of conditions. As described by the WHO report International Perspectives on Spinal Cord Injury (WHO 2013), SCI refers to damage to the spinal cord arising from trauma (such as a car crash), or from non-traumatic disease or degeneration (such as tuberculosis), and encompasses both a baby born with spina bifida and a construction worker who falls from scaffolding.

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Topics: Science Alert, International Spinal Cord Society (ISCoS), Spinal Cord Injury (SCI)

Science Alert: Children with specific bladder care needs

November 21, 2017

Urinary tract anomalies are sometimes seen in children, and many of them require active treatment to achieve continence. Vesicoureteral reflux and/or a neurogenic bladder secondary to meningomyelocele (e.g. spina bifida) are two examples that require swift action.

Catheterization is sometimes a suitable solution and new research has studied the need for local anesthetic associated with catheterization. A meta-analysis combined many study results and concluded that the effect of local anesthetic was limited.

Sometimes, catheterization is not possible through the urethra and a continent catheterizable channel is surgically created. Different procedures (e.g. Mitrofanoff) can be used and two new studies look into the complications associated with this kind of surgery. Both studies conclude that surgical procedures should only be used in children who cannot perform urethral catheterization, because surgical revisions and long-term complications are common.

Another, maybe more far-fetched, solution to these children's problems is the use of stem cell therapy. A new review summarizes the available evidence for stem cell therapy and show that the use of bone marrow stem cells has potential in bladder tissue regeneration.

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Topics: Science Alert, Urinary Tract Infection (UTI), Neurogenic bladder, Catheter-associated UTI (CAUTI)

Science Alert: Urinary Tract Infection (UTI) – Are Probiotics the answer?

November 7, 2017

Urinary tract infections (UTIs) are a heavy burden on the healthcare system today. UTIs are also one of the most common complications among people living with a neurogenic bladder, causing significant complications and health hazards. New clinical research investigates the clinical problem and demonstrates that UTIs are still among the leading causes of death in people with a neurogenic bladder.

On average, people with a neurogenic bladder experience 2 UTI events every year, requiring repeated antibiotic treatments. Frequent use of antibiotics is one of the main contributors to the high prevalence of antibiotic-resistant bacteria today, and as a result, UTIs are getting more expensive and more difficult to treat. As a consequence, there is a major focus in clinical research on the search for non-antibiotic prophylactic treatment for UTIs.

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Topics: Science Alert, Urinary Tract Infection (UTI), Neurogenic bladder, Catheter-associated UTI (CAUTI)